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A highly efficient method for the synthesis of 2-hydroxy-2,3-dihydrofuran derivatives from 1,4-enediones and phenacyl pyridinium halides via a domino reaction has been developed. At the same time, we also synthesize the novel 4-(1H-pyrazol-4-yl)pyridazine skeleton.doi:10.1039/c5ob00163c pmid:25821120 fatcat:koofty4amndj5mzv2arrznpmxe