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Pseudo-neonatal adrenoleukodystrophy (P-NALD) is a neurodegenerative disorder caused by acyl- CoA oxidase 1 (ACOX1) deficiency with subsequent impairment of peroxisomal fatty acid βoxidation, accumulation of very long chain fatty acids (VLCFAs) and strong reduction in peroxisome abundance. Increase in peroxisome number has been previously suggested to improve peroxisomal disorders, and in this perspective, the present work was aimed at exploring whether modulation of peroxisomes abundance coulddoi:10.4236/health.2013.51009 fatcat:nok2pcyj65e77khizabs2gmtam