SPECTRAL CHARACTERIZATION, HIRSHFELD SURFACE ANALYSES AND ANTIFUNGAL ACTIVITY OF TWO ISOMERIC HETEROCYCLIC COMPOUNDS CONTAINING QUINOXALINE AND OXAZOLIDINONE MOIETIES

Ballo Daouda, Mohamadou Lamine Doumbia, Tuncer Hökelek, Fakhreddine Zemmouri, Kablan Claude, Allal Douira, Nada Kheira Sebbar
2020
Two isomeric heterocyclic compounds containing quinoxaline and oxazolidinone moieties have been prepared through the reaction alkylation of 3-phenyl-quinoxalin-2-one by bis-dichloroethylamine hydrochloride under liquid-solid phase transfer catalysis conditions. Their structures have been characterized on the basis of spectral data (IR and NMR) confirming the results obtained by single-crystal X-ray diffraction analysis. Furthermore, the closest contacts between the active atoms of the compounds
more » ... were identified through Hirshfeld surface analyses. In addition, their antifungal activity has also been evaluated.
doi:10.48369/imist.prsm/jmch-v19i1.22067 fatcat:jextzvppzrbg3gzrc7z4zc6n34