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The role of environmental exposures and gene-environment interactions in the etiology of systemic lupus erythematous
2022
Systemic lupus erythematosus (SLE) is a complex, chronic autoimmune disease, whose etiology includes both genetic and environmental factors. Individual genetic risk factors likely only account for about one-third of observed heritability among individuals with a family history of SLE. A large portion of the remaining risk may be attributable to environmental exposures and gene-environment interactions. This review focuses on SLE risk associated with environmental factors, ranging from chemical
doi:10.1111/joim.13448
pmid:35143075
fatcat:3lt5n3o22ngr3ntud2qlgsmewu