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Interferon-stimulated genes and their role in controlling hepatitis C virus
2013
Journal of Hepatology
Infections with the hepatitis C virus (HCV) are a major cause of chronic liver disease. While the acute phase of infection is mostly asymptomatic, this virus has the high propensity to establish persistence and in the course of one to several decades liver disease can develop. HCV is a paradigm for the complex interplay between the interferon (IFN) system and viral countermeasures. The virus induces an IFN response within the infected cell and is rather sensitive against the antiviral state
doi:10.1016/j.jhep.2013.07.033
pmid:23933585
fatcat:jk5bbgl5zfa6jbybny3yr53ue4