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Several studies showed that obesity and fat deposition in the tissues along with inflammatory response may induce insulin resistance and finally type II diabetes. Salsalate can inhibit IKK and NF-KB inflammatory pathway. The aim of this study was to determine the efficacy of salsalate as an anti-inflammatory drug in blood glucose decrement of diabetics. Methods: This was a double blind case-control trial. Sixty newly diagnosed diabetic patients were randomized in the drug and the placebodoaj:4f17a5c68e364cbd85e08c1146b96560 fatcat:hdf5bxwupnc6nf3ba3pqkcqsli