Obstructive sleep apnea (OSA) and bruxism are widely recognized as common forms of sleep obstruction in modern everyday life. The most representative and conventional treatment method using continuous positive airway pressure has a critical problem owing to its high inconvenience. A relatively modern alternative solution is the mandibular advancement device, but it still has no monitoring function for patient compliance. Therefore, this research proposes Sleep Guard (s-Guard), a multisensor

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... dded OSA monitoring intraoral appliance device based on Internet-of-Things technology. Relevant health information monitoring sensors, such as temperature, gyroscope, accelerometer, and SpO2 sensors, were embedded for real-time health monitoring. Results showed an average transmission speed of 91,870.19 bytes per second, a successful connection check rate of 100%, and a wireless data stream error rate of 0.1%. Overall, the actual speed, connection, and error test results revealed the robust functioning of s-Guard in real monitoring scenarios. This research is envisioned to greatly enhance patient compliance when treating OSA or bruxism and is also expected to motivate other sensors to be embedded in our proposed model for the application of other disease areas.