Nobutaka Ohta, Hiroshi Terada, Masaru Nakano, Tomomi Ushiyama, Atsushi Tajima, Kazuki Kawabe, Hiroshi Nagae, Akihiko Suzuki, Masataka Hirai, Hiroaki Masuda, Takashi Mitsuhashi
1991 Chemotherapy  
Cefepime, a newly developed cephalosporin, was administered to 27 patients with UTI, at a dose of 0.5 or 1.0 g i.v. twice a day. Of the 2 patients with acute uncomplicated pyelonephritis, one was evaluated as effectively treated according to the attending physicians. On application of the criteria of the Japanese UTI Committee, only one case was evaluable and was assessed moderately effectively treated. Of the 25 cases of complicated UTI, the efficacy rate according to the attending physicians
more » ... valuation was 80.0 %. Twenty out of 25 cases met the criteria for evaluability of the Japanese UTI Committee. The clinical efficacy was excellent in 7, good in 8 and poor in 5 cases, with an overall efficacy rate of 75.0 %. During treatment, transient elevation of liver enzymes in 4 patients and abnormalities of differential white blood cell count in 2 patients were observed.
doi:10.11250/chemotherapy1953.39.supplement2_469 fatcat:alvfpirrkfekxbvmzg3z7uphuu