Can adaptive treatment improve outcomes in family-based therapy for adolescents with anorexia nervosa? Feasibility and treatment effects of a multi-site treatment study

James Lock, Daniel Le Grange, W. Stewart Agras, Kathleen Kara Fitzpatrick, Booil Jo, Erin Accurso, Sarah Forsberg, Kristen Anderson, Kate Arnow, Maya Stainer
2015 Behaviour Research and Therapy  
Objective: To systematically review the literature reporting outcomes of augmentative Family-Based Treatment (FBT) interventions for adolescents with restrictive eating disorders (EDs). Method: Articles were identified through a systematic search of five electronic databases (PsycINFO, MEDLINE, EMBASE, CINAHL, Cochrane Database). Results: Thirty articles were included, reporting on FBT augmentations featuring adjunctive treatment components, modified treatment structure and/or content with
more » ... ence to FBT principles, and adaptations allowing FBT delivery in different settings. All reported significant improvements in weight and/or ED symptoms at end-of-treatment, although few compared augmentative and standard FBT interventions and good quality follow-up data was generally lacking. Conclusions: There is early evidence for the effectiveness of augmentative FBT-based approaches in facilitating weight and/or ED symptom improvements for adolescents with restrictive EDs. There remains a lack of robust evidence demonstrating superior effects of such approaches over standard FBT and further controlled studies are required to expand on the current evidence.
doi:10.1016/j.brat.2015.07.015 pmid:26276704 pmcid:PMC4573312 fatcat:ksqsvvndgresxbn3pv5zbtg7a4