Estudo farmacológico do Heterothalamus brunioides: dose letal, atividade geral e sistema nervoso central

Adriana Pizzutti dos Santos, Juliane Lavarda, Claúdio Sityá, Paulo Ricardo Führ, Ana Maria Chagas
1987 Ciência e Natura  
Heterothalamus brunioides Less is a native herb in Santaninha da Boa Vista (RS), and it is used in popular medicine to decrease toxilogical effect caused by snake bites. The objective of this study was to evaluate the lethal dosis as well as the effects of the aquous extract of this plant upon the general activity and central nervous system. The lethal dosis on Wistar rats was 143,2 mg/kg of the cold aquous extract and when it was boiled none toxicological effect was observed. So, this
more » ... . So, this substance is thermolabile. Since the general activity was not effects by the use of this drug, there is no non-indication for its recomendation. The effect upon the central nervous system is characterized by depression.
doi:10.5902/2179460x25467 fatcat:oi4n6q6krzclvdu3cti52lleji