Blistering mucocutaneous disease of oral cavity Pemphigus vulgaris-8 year study in Nalgonda population

P Pavan, Madhusudan Rao, Pavan Kulkarni, Srk Nandan, Shyam Reddy, M Keerthi
2017 unpublished
Autoimmune disorders are conditions in which autoantibodies are directed against a single organ or tissue resulting in localized tissue damage. Pemphigus includes a group of autoimmune blistering diseases of skin and mucous membranes characterized by intra dermal blisters and immunologically by finding of circulating immunoglobulin G antibody directed against the cell surface of keratinocytes. Objectives: To analyze age distribution of Pemphigus vulgaris, prevalence among males and females,
more » ... es and females, predominant oral site and clinical presentation. Materials and methods: A retrospective study of 31 cases of Pemphigus vulgaris obtained over a period of 8 years from January 2008 to September 2015 in the Department of Oral Pathology, Kamineni Institute of Dental Sciences was designed. Clinical details of age, sex, intraoral distribution and oral presentation were noted.