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Environmental control of microtubule-based bidirectional cargo transport
2014
Europhysics letters
Inside cells, various cargos are transported by teams of molecular motors. Intriguingly, the motors involved generally have opposite pulling directions, and the resulting cargo dynamics is a biased stochastic motion. It is an open question how the cell can control this bias. Here we develop a model which takes explicitly into account the elastic coupling of the cargo with each motor. We show that bias can be simply controlled or even reversed in a counterintuitive manner via a change in the
doi:10.1209/0295-5075/107/18004
fatcat:jyj5hk3mwrcb5hh722nh2yziiy