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Cortical patterning of abnormal morphometric similarity in psychosis is associated with brain expression of schizophrenia related genes: Supplementary Information
[article]
2018
bioRxiv
pre-print
Schizophrenia has been conceived as a disorder of brain connectivity but it is unclear how this network phenotype is related to the emerging genetics. We used morphometric similarity analysis of magnetic resonance imaging (MRI) data as a marker of inter-areal cortical connectivity in three prior case-control studies of psychosis: in total, N=185 cases and N=227 controls. Psychosis was associated with globally reduced morphometric similarity (MS) in all 3 studies. There was also a replicable
doi:10.1101/501494
fatcat:qpbyqnvhwjam7hjs2wvlzev2hm