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The authors present the results of a questionnaire survey conducted in serological laboratories in 60 dermatovenerology enterprises in the subjects of the Russian Federation on the use of up-to-date methods for the determination of Class M antibodies for the diagnostics of early syphilis. It was revealed that treponemal specific Class M antibodies were determined in 86.67% of laboratories: the EIAIgM method was used in 86.67% of laboratories, IBIgM - in 18.33%, and PHTIgM - in 6.67% ofdoi:10.25208/0042-4609-2015-0-4-83-89 doaj:65bdf0701ed1495ba14c0762214850ac fatcat:bsanj54r45hh3nbl7gvme66cty