Objective: To observe the application effect of painless gastrointestinal endoscopy in the treatment of digestive diseases and provide reference for clinical application. Methods: A total of 144 patients who underwent gastrointestinal endoscopy in the Department of Gastroenterology were randomly divided into two groups, 72 in each group. Patients in the control group underwent routine gastrointestinal endoscopy. The patients in the observation group underwent painless gastrointestinal

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... The operation time, examination results, pain and adverse reactions of the two groups were compared. Results: The physiological indexes (heart rate, blood pressure, etc.) of the observation group were lower than those of the control group before and after the examination. The observation group had short operation time, mild pain and low adverse reaction rate. The difference was statistically significant (P <0. 05). Conclusion: Painless gastrointestinal endoscopy has the characteristics of small trauma, mild pain, low adverse reaction rate and good compliance. It can be used as an ideal method for gastrointestinal examination of gastroenterology.