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The Integrated Genomic Landscape of Thymic Epithelial Tumors
2018
Cancer Cell
Thymic epithelial tumors (TETs) are one of the rarest adult malignancies. Among TETs, thymoma is the most predominant, characterized by a unique association with autoimmune diseases, followed by thymic carcinoma, which is less common but more clinically aggressive. Using multi-platform omics analyses on 117 TETs, we define four subtypes of these tumors defined by genomic hallmarks and an association with survival and World Health Organization histological subtype. We further demonstrate a
doi:10.1016/j.ccell.2018.01.003
pmid:29438696
pmcid:PMC5994906
fatcat:5khwqh4jsjdyhilaclblvv7a7q