Experience of Using Bedaquiline in a Young Child with Drug Resistant Tuberculosis and Concurrent Primary Immunodeficiency

T. I. Danilova, N. А. Barmina, E. S. Borisova, L. А. Maksimova, Yu. V. Kornev
2021 Tuberkulez i Bolezni Lëgkih  
The article describes a clinical case of the treatment of a young child with a complicated course of tuberculosis with multiple localizations and concurrent primary immunodeficiency. The new anti-tuberculosis drug of bedaquiline was successfully used in the treatment regimen. The child received bedaquiline for 6 months without any adverse events, after 2 months no acid-fast mycobacteria were detected, there were pronounced positive radiological changes which remained until the end of treatment.
more » ... This clinical case provides evidence that bedaquiline can be used safely and effectively in MDR TB chemotherapy regimens in children under 5 years of age.
doi:10.21292/2075-1230-2021-99-8-47-53 fatcat:ssl7h3ycb5fb7nvfghohmesgdu