In our experiments we followed the histological and physiological modifications induced by the action of the insecticide Carbetox at the skin and liver level of Rana Ridibunda. Carbetox is an organophosphate insecticide commonly used to control mosquitos and other flying insects. The animals used in the experiment were divided in three experimental lots: one lot of control individuals and two experimental lots in which the frogs were kept in two acuaterrarios with a 0.01 ml/l and respectively

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... 1 ml/l Carbetox. We began sacrificing them at four and five weeks from the start of the experiment. We observed a hypertrophied mucose gland of the tegument, an increased volume of hepatocytes as well as increased reserve of lipofuscin; a decrease a number of erythrocytes as well as an increase a glycaemia indices was observed.