Measurement of regional pulmonary blood flow with PET

D P Schuster, J D Kaplan, K Gauvain, M J Welch, J Markham
1995 Journal of Nuclear Medicine  
We have previously reported a method for measuring regional pulmonary blood flow (PBF) in experimental animals using 15O-water and PET. The method requires withdrawing blood from the pulmonary artery during the PET scan, so that the input function can be estimated for the one-compartment model used to analyze the data. The purpose of the present study was to modify and validate this technique for a more general use in humans.
pmid:7884497 fatcat:c5dtjscxrvhuff2htwotig4bvm