Impact of Polymer Nanoparticles on DPPC Monolayer Properties

Alexey Bykov, Olga Milyaeva, Alexander Akentiev, Maria Panaeva, Nikolaj Isakov, Reinhard Miller, Boris Noskov
2022 Colloids and Interfaces  
The application of surface rheology and Brewster angle microscopy on mixed monolayers of DPPC and polymeric nanoparticles (cationic and anionic) showed that the sign of the particle charge affects the dynamic properties of the monolayers less than the nanoparticles' ability to aggregate. Under almost physiological conditions, the effect of nanoparticles on the elasticity of DPPC monolayer is insignificant. However, the particles prevent the surface tension from decreasing to extremely low
more » ... . This effect could affect the functionality of pulmonary surfactants.
doi:10.3390/colloids6020028 doaj:249bbc6d32c442b08ead20ce8b176e18 fatcat:jf32rrtnrvfwvacfsvutnka3pm