Utility and accuracy of perceptual voice and speech distinctions in the diagnosis of Parkinson's disease, PSP and MSA-P

Nick Miller, Uma Nath, Emma Noble, David Burn
2017 Neurodegenerative Disease Management  
Aims To determine if perceptual speech measures distinguish people with Parkinson's (PD), multiple system atrophy with predominant parkinsonism (MSA-P) and progressive supranuclear palsy (PSP). Methods Speech-language therapists blind to patient characteristics employed clinical rating scales to evaluate speech/voice in 24 people with clinically diagnosed PD, 17 with PSP, 9 with MSA-P, matched for disease duration (mean 4.9 years, SD 2.2). Results No consistent intergroup differences appeared
more » ... specific speech/voice variables. People with PD were significantly less impaired on overall speech/voice severity. Analyses by severity suggested further investigation around laryngeal, resonance and fluency changes may characterise individual groups Conclusion MSA-P and PSP compared to PD were distinguished by severity of speech/voice deterioration, but individual speech/voice parameters failed to consistently differentiate groups.
doi:10.2217/nmt-2017-0005 pmid:28632098 fatcat:fck2uarmw5cojeo7isfji234ni