Effects of Water Consumption on Kidney Function and Excretion

Ivan Tack
2010 Nutrition Today  
Water homeostasis depends on fluid intake and maintenance of body water balance by adjustment of renal excretion under the control of arginine vasopressin hormone. The human kidney manages more efficiently fluid excess than fluid deficit. As a result, no overhydration is observed in healthy individuals drinking a large amount of fluid, whereas a mild hydration deficit is not uncommon in small-fluid-volume (SFV) drinkers. Small-fluid-volume intake does not alter renal function but is associated
more » ... but is associated with an increased risk of renal lithiasis and urinary tract infection. In that case, increasing fluid intake prevents recurrence. The benefit of increasing fluid intake in healthy SFV drinkers had never been studied until now. Two recent studies from Danone Research indicate that increasing water intake in such people leads to a significant decrease of the risk of renal stone disease (assessed by measuring Tiselius' crystallization risk index). Because renal lithiasis and urinary tract infection prevalence are quite high in western countries, this preliminary observation supports the interest of an approach based on primary prevention using voluntary increase in water-based fluid consumption in SFV drinkers. Complementary studies are required to determine other clinical impacts of SFV intake and to evaluate the benefits of increasing fluid intake. Nutr Today. 2010;45(6S):S37-S40
doi:10.1097/nt.0b013e3181fe4376 fatcat:25t5t3sabvbqpmkubtz45pmctm