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Evaluation of the profile of inflammatory cytokines, through immunohistochemistry, in the skin of patients with allergic contact dermatitis to nickel in the acute and chronic phases
2018
Anais Brasileiros de Dermatologia
Allergic contact dermatitis to ion nickel (Ni+2) is an inflammatory dermatosis, common in industrialized countries. It involves the activation of nickel-specific T-cells, followed by proliferation and induction of a mixed profile of both proinflammatory and regulatory cytokines, suggesting that several T-cell subtypes (helper - Th and cytotoxic - Tc) are involved. A broader understanding of the cytokine profile may lead to new therapeutic approaches. This study aimed to analyze the cytokines
doi:10.1590/abd1806-4841.20187126
pmid:33261757
pmcid:PMC6256231
fatcat:ylrfeeaewbfepnmmpmiograkrq