Study of lipid profile changes and histopathology examination of heart under immobilization stress with static magnetic field exposure in rats

Shanmugapriya, Sarumathi, Saravanan
2012 International Journal of Environmental Biology   unpublished
The presentation in this study is focused on the effects of acute stress and exposure to static magnetic field (SMF) on rats. The plasma corticosterone, lipid profile, Total cholesterol, High Density Lipoprotein, Very Low Density Lipoprotein, Low Density Lipoprotein, Triglycerides, Free Fatty Acids (TC, HDL, VLDL, LDL, TGL and FFA) in plasma, liver, kidney and brain of acute stress as well as SMF exposed rats were analysed. The exposure of rats to immobilization stress (restraining the animals
more » ... y placing in 20cm х 7cm plastic tubes for 2h per day for 21 days) and exposure to SMF (128mT, 1h/day during 21 consecutive days) increased the activities of lipid profiles and decreased the activities of HDL in plasma, liver, kidney, heart and brain. Our results show that acute stress produced changes in Blood Pressure (BP) that may be associated with increased sympathetic activity and there is an adverse effects occurs when both the acute stress and SMF are exposed to the rats which may mimic the people working with stress in the field of computers and in factories with magnetic fields induced by electrical appliances and instruments which may increase the stress level and alter the lipid profile which may lead to cardiovascular diseases evidenced by histopathological changes in the heart.