SAT0116 The study of baseline serum sicam-1 and cxcl13 levels in predicting response to tumor necrosis factor-Α inhibitor therapy in patients with rheumatoid arthritis

X. Ye, J. Zhao, Z. Zhang
2018 Saturday, 16 JUNE 2018   unpublished
population census of the National Institute of Statistics, with an estimated prevalence of RA of 0,5% (women: 0,8%, men:0,2%). Crude and adjusted rates of the solid tumors were calculated. The trend was analyzed by Generalized Linear Model (GLM). Results: 338.343 RA hospital admissions were detected in the study period, being 18.401 (5,4%) due to solid tumors. The main clinical-demographic characteristics are shown in the next table. Total Women Men P value N (%) 18.401 (5,4) 8689 (3,8) 9712
more » ... 6) P<0,001 Age, mean (SD) 69,98 (11,21) 68,62 (12,3) 71,20 (9,99) P<0,001 In-hospital exitus n (%) 2455 (13,34) 1035 (11,9) 1420 (14,62) P<0,001 Charlson Index, mean (SD) 5,72 (2,95) 5,63 (2,95) 5,80 (2,95) P<0,001 Stay, mean (SD) 10,94 (11,6) 10,76 (11,6) 11,1 (11,77) P=0,051 The solid tumor adjusted rate during the study period was 647,53/10 5 inhabitants/ yr (366,97/10 5 in women and 1792,99/10 5 in men; relative risk men:women =4,8). This rate increased from 305,in women). The annual age-adjusted rate increased significantly: 7,37% (6,52% in men and 8,02% in women; p≤0,001). figure1 Conclusions: There was an increasing incidence of hospital admissions due to solid tumors in RA in Spain during the period 1999-2015. An annual rate increase of 7.37%, is estimated.
doi:10.1136/annrheumdis-2018-eular.6015 fatcat:nfqf2mm7mzadxehq5ukisgo7py