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Inference with viral quasispecies diversity indices: clonal and NGS approaches
2014
Computer applications in the biosciences : CABIOS
Given the inherent dynamics of a viral quasispecies we are often interested in the comparison of diversity indices of sequential samples of a patient, or in the comparison of diversity indices of virus in groups of patients in a treated versus control design. It is then important to make sure that the diversity measures from each sample may be compared with no bias and within a consistent statistical framework. In the present report we review some indices often used as measures for viral
doi:10.1093/bioinformatics/btt768
pmid:24389655
fatcat:arpntvvm65cvxopkq3kulvr7va