Symptomatic Dystonias Associated with Structural Brain Lesions: Report of 16 Cases

Vladimir S. Kostià, Marina Stojanovié-Svetel, Aleksandra Kacar
1996 Canadian Journal of Neurological Sciences  
ABSTRACT:Background:Symptomatic (secondary) dystonias associated isolated lesions in the brain provide insight into etiopathogenesis of the idiopathic form of dystonia and are a basis for establishing the possible correlation between the anatomy of a lesion and the type of dystonia according to muscles affected.Methods:In 358 patients with differently distributed dystonias, a group of 16 patients (4.5%) was encountered in whom dystonia was associated with focal brain lesions.Results:Of the 16
more » ... Results:Of the 16 patients, 3 patients had generalized, 3 segmental and 4 hemidystonia, while the remaining 6 patients had focal dystonia. The most frequent etiologies were infarction in 7, and tumor in 4 patients. These lesions were usually found in the lenticular and caudate nucleus, thalamus, and in the case of blepharospasm in the upper brainstem.Conclusions:Our results support the suggestion that dystonia is caused by a dysfunction of the basal ganglia.
doi:10.1017/s0317167100039184 fatcat:vcsmo35zffbyri4qhsjpddoaeu