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This research determined the pathological effects of Moringa oleifera seed powder, a natural alternative to alum, used as a water purifier in fish culture enclosure in Nigeria. The histological changes in gill, liver, skin and kidney of fingerling and adult Nile tilapia Oreochromis niloticus exposed to aqueous extract of Moringa oleifera seed at different sub-lethal concentration under static bioassay procedure are described. There were pathologic lesions observed which included differentdoi:10.7827/turkishstudies.10064 fatcat:fhd6apgz3rai7afyovxpwlyt2q