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Differential localization of Th1 and Th2 cells in autoimmune gastritis
1998
International Immunology
The vast majority of CD4 ⍣ T cells infiltrating into gastric mucosa (GM) and in the draining (gastric) lymph node (GLN) shows an activated/memory phenotype, CD45RB low L-selectin low CD44 high , in neonataly thymectomized BALB/c mice bearing autoimmune gastritis (AIG), indicating that these cells are actively involved in this disease. CD4 ⍣ T cells sort-purified from GLN expressed mRNAs encoding for both IFN-γ and IL-4. However, those infiltrating into GM expressed very low levels of IL-4 mRNA,
doi:10.1093/intimm/10.9.1325
pmid:9786432
fatcat:5kyz7go4unaidp3on64ohveaza