Body temperature is an important homeothermic autoregulation of humans. Body temperature is usually controlled by autonomic nervous system (ANS). When a person has suffered a virus or bacterial infection, it causes fever. The ANS rises the body temperature by tachycardia and cutaneous vasomotion. The common non-invasive indication for ANS is based on heart rate variability (HRV) and pulse rate variability (PRV). However, these two methods are limited by the timescale of time series.

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... s PRV (iPRV) was proposed as a surrogate of HRV in frequency domain and breaks the restriction of timescale. In this paper, thirty subjects were recruited for the study; the body temperature and the photoplethysmography (PPG) signal were acquired in supine position for ten minutes. Fifteen fever subjects, whose body temperature was higher than 37.9 °C, are in Group Fev., the others are in Group Ctr. The results show that the power of iPRV in normalized low frequency (nLF) in Group Fev.(0.63±0.13, p<0.05) was significantly higher than that in Group Ctr.(0.47±0.16). And the power of iPRV in normalized high frequency (nHF) in Group Fev.(0.38 ±0.13, p<0.05) was significantly lower than that in Group Ctr.(0.54±0.16). Besides, the nVHF might have a potential for indicating the peripheral circulation and providing more information about body regulation.