A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf
.
Nkx2-1: a novel tumor biomarker of lung cancer
2012
Journal of Zhejiang University SCIENCE B
Nkx2-1 (Nkx homeobox-1 gene), also known as TTF-1 (thyroid transcription factor-1), is a tissue-specific transcription factor of the thyroid, lung, and ventral forebrain. While it has been shown to play a critical role in lung development and lung cancer differentiation and morphogenesis, molecular mechanisms mediating Nkx2-1 cell- and tissue-specific expression in normal and cancerous lungs have yet to be fully elucidated. The recent identification of prognostic biomarkers in lung cancer,
doi:10.1631/jzus.b1100382
pmid:23125078
pmcid:PMC3494024
fatcat:bau7ijt4ufdpla7clykwh4piju