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and purpose: Gliomas are very heterogeneous tumors, glioma grading is currently based on the histologic assessment. With noninvasive measurement of vascular permeability by CT Perfusion (CTP) multiple perfusion parameters which can be obtained with a single acquisition the aim of this study was to find the most sensitive and specific CTP parameters and their cutoffs that can be used to differentiate between low and high grade brain gliomas. Material and methods: Twenty-five patients weredoi:10.1016/j.ejrnm.2015.07.002 fatcat:ns7rly5l5jek7jnhsffpswzzzi