Diversity of rodents, hantavirus and its relationship to public health

Camilo Guzmán, Salim Mattar, Alfonso Calderón
2015 Salud Uninorte   unpublished
The order Rodentia comprises the group of mammals with the greatest diversity of living species that are natural hosts and reservoirs of hantavirus. Guests are natural reservoirs and hantavirus. All hantavirus that cause cardiopulmonary syndrome in the Americas are linked to the subfamily Sigmodontinae. Each hantavirus has affinity for a specific rodent host. In Korea the first Hantaan virus was isolated in 1976 from a lung culture of field mouse Apodemus agrarius. In 1978, the Seoul virus was
more » ... he Seoul virus was identified from Rattus norvegicus. In Finland, the Puumala hantavirus from Myodes glareolus lung. In 1993, hantavirus Dobra-va from Apodemus flavicolis was isolated in Slovenia and in 1982 the first hantavirus in the Americas called Prospect Hill isolated form Microtus pennsylvanicus, which resulted nonpathogenic and for this reason it was believed that the American hantavirus were non-pathogenic. However, in 1993 a mysterious lung disease began spreading in Four Corners (USA), the patients suddenly became ill and many died due to shock and/or lung edema; these early symptoms were not associated with hantavirus but a virus subsequently isolated from Peromyscus maniculatis was a new virus now known as hantavirus without name was cause of this outbreak. In South America hantavirus have been reported in different natural hosts. In Colombia between 2004 and 2006 the first serological studies in the Colombian Caribbean, where they reported the circulation of hantavirus in humans and rodents, were published. However, hantavirus is not considered a reportable disease and probably currently it is in epidemiological silence.