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Identification of the active substance and mechanisms of CFF-1 for treatment of prostate cancer based on network pharmacology, virtual screening, and molecular dynamics simulation
Background CFF-1 is an effective treatment option for prostate cancer patients, but there is a lack of network pharmacology research on its molecular mechanism. Methods Based on bioavailability and drug-likeness, the main active ingredients of CFF-1 were obtained through the Traditional Chinese Medicine System Pharmacology (TCMSP) database. The GeneCard, OMIM, PharmGKB, Therapeutic Targets database, and DrugBank were used to construct prostate cancer target gene sets. Construct andoi:10.21203/rs.3.rs-401623/v1 fatcat:sj3axi5tjjdkvgutnjqsgpzspq