Allergen Specificity in Specific IgE Cutoff

Ann-Marie Malby Schoos, Simone Møbius Hansen, Frederikke Rosenvinge Skov, Jakob Stokholm, Klaus Bønnelykke, Hans Bisgaard, Bo Lund Chawes
2020 JAMA pediatrics  
Discussion | Use of legal performance-enhancing substances among young adult men (aged 18-26 years) was significantly prospectively associated with anabolic-androgenic steroid use at 7-year follow-up (aged 24-32 years). To our knowledge, this is the first longitudinal investigation of this association among a nationally representative sample. Results suggest that legal performance-enhancing substance use may serve as a gateway to anabolic-androgenic steroid use. This has significant
more » ... for regulation of legal performance-enhancing substances, which are relatively common among the adolescent and young adult population, 1,2 accessible over the counter, and unregulated by the US Food and Drug Administration. 4 The notion that use of legal performance-enhancing substances may lead to a 3-fold increased risk for future use of illicit anabolicandrogenic steroids provides support for increasing state and federal regulation of these products. Limitations to this study include self-reported data, lifetime (as opposed to 12-month) assessment of anabolic-androgenic steroids use, inability to distinguish between prescription or nonprescription anabolicandrogenic steroid use, and inability to analyze associations between specific substances (ie, creatine monohydrate or androstenedione) and anabolic-androgenic steroid use. Conclusions | The current study suggests that use of performance-enhancing substances among young men may increase vulnerability for anabolic-androgenic steroid use in young adulthood. Health care professionals should monitor and screen for anabolic-androgenic steroid use among adult men who have previously used legal performance-enhancing substances and refer patients to mental health and substance abuse treatment when appropriate.
doi:10.1001/jamapediatrics.2020.0944 pmid:32421160 pmcid:PMC7235915 fatcat:mdmgrwoyrrdxlhwdqp3obnkkny