Study of the sensitivity of Enterococcus faecalis to the methanolic extracts of Solanum incanum L

Mwaba Mulubwa Jean Jacques, Faculty of Pharmaceutical Sciences, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo (DRC), Mwenda Kalenga Lydia, Ngulu N'sasi Arthur, Faculty of Pharmaceutical Sciences, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo (DRC), Faculty of Veterinary Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo (DRC)
2017 The Journal of Medical Research  
Context: Enterococci are known germs capable of causing urinary infections, peritonitis, intra-abdominal abscesses, nosocomial bacteremia. These germs are today experiencing several forms of resistance to antibiotics sold on the market in the DRC. Goal: The aim of this work was to determine the sensitivity of enterococcus faecalis to the total extracts of Solanum incanum L., an effective reputed plant in traditional medicine for the treatment of infections caused by Enterococcus faecalis in the
more » ... cus faecalis in the city of Lubumbashi, DRC. Material and methods: The preliminary phytochemical screening was carried out on the total extracts for the identification of phytochemicals active in the plant and the strain of Enterococcus faecalismade it possible to carry out the sensitivity tests. Results: The results reveal the presence of alkaloids, flavonoids, saponins, steroids and tannins. Biological tests reveal a sensitivity of Solanum incanum L. to total extracts of this plant. Conclusion: The analyzes carried out show that this plant used in Congolese traditional medicine is effective against the infections caused by Enterococcus faecalis. The subsequent fractionation of the total extracts and the evaluation of the antibacterial activity of the fractions which will be obtained will make it possible to demonstrate the active principles responsible for this antibacterial activity.
doi:10.31254/jmr.2017.3511 fatcat:wekuflff3beobmxdn53mn7en2m