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Human LDL Structural Diversity Studied by IR Spectroscopy
2014
PLoS ONE
Lipoproteins are responsible for cholesterol traffic in humans. Low density lipoprotein (LDL) delivers cholesterol from liver to peripheral tissues. A misleading delivery can lead to the formation of atherosclerotic plaques. LDL has a single protein, apoB-100, that binds to a specific receptor. It is known that the failure associated with a deficient protein-receptor binding leads to plaque formation. ApoB-100 is a large single lipid-associated polypeptide difficulting the study of its
doi:10.1371/journal.pone.0092426
pmid:24642788
pmcid:PMC3958539
fatcat:r7sdepnrbrafjhdqdoqigrvacq