Aim of study. To reveal peculiarities in topography and quantitative content of subcutaneous tissue in adolescents with different values of BMI and sexual dimorphism index. Material and methods. A total of 498 male and female adolescents of European ethnicity were studied. The methods applied were anthropometry, caliperometry, ultrasound scanning of subcutaneous tissue, the method for BMI and sexual dimorphism calculation by J.M. Tanner (1951) and statistical analysis. Results. Sexual inversion

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... manifested by gynecomorphy was revealed in 11.0% male patients and andromorphy was observed in 22.5% female patients. Caliperometry provided the following results: obesity in male adolescents lead to a statistically significant increase in the skinfold thickness as compared to subjects with normal BMI in the following areas: abdomen – 39mm [38.6; 41.17] against 13.15mm [12.57; 16.8] (2.97-fold); rear shoulder – 18.25mm [16.94; 20.13] against 6.25mm [5.47; 8.58] (2.90-fold); back – 28mm [26.13; 29.98] against 10.5 [9.93; 12.67] (2.67-fold). Female adolescents with obesity were noted to have statistically significant increase in skinfold thickness in the following areas: front shoulder – 21.3mm [20.73; 23.46] against 5.7mm [4.61; 7.39] (3.73-fold); above pectoral muscles – 15.0mm [13.25; 20.12] against 5.7mm [4.13; 7.0] (2.63-fold); abdomen: 37.0mm [31.18; 39.42] against 16.0mm [11.10; 18.54] and thigh: 42.3mm [40.13; 45.64] against 18.3mm [17.92; 20.72] (2.31-fold). It has been shown that assessment of topology and thickness of skinfolds on certain body parts depending on the BMI and morphotype of subjects will make it possible to reveal their predisposition to sexual inversion and include them into the risk group. Conclusion. Through the method of caliperometry (identical sonography data) and anthropometry, a pattern in skinfold distribution depending on the morphotype has been determined. Target biomarkers for topography and thickness of skinfolds characteristic to subjects with sexual inversion have been studied.