Production and response to interleukin 2 in vitro and in vivo after bone marrow transplantation in mice

V J Merluzzi, K Welte, K Last-Barney, R Mertelsmann, L Souza, T Boone, D M Savage, D Quinn, R J O'Reilly
1985 Journal of Immunology  
Lymphoid cells from bone marrow radiation chimeras do not produce normal levels of IL 2 but are capable of responding to IL 2 in mitogenic and cytotoxic assays in vitro. The administration of recombinant human IL 2 into host mice that have received allogeneic, H-2-compatible marrow did not enhance mortality.
doi:10.4049/jimmunol.134.4.2426 fatcat:q6mlpnhyefem3ni3u2kx7i7k3e