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2 ABSTRACT Purpose To determine the feasibility of MRI texture analysis as a method of quantifying subchondral bone architecture in knee osteoarthritis (OA). Methods Asymptomatic subjects aged 20-30 (group 1, n=10), symptomatic patients aged 40-50 (group 2, n=10) and patients scheduled for knee replacement aged 55-85 (group 3, n=10) underwent high spatial resolution T1 weighted coronal 3T knee MRI. Regions of interest were created in the medial (MT) and lateral (LT) tibial subchondral bone fromdoi:10.1007/s00330-015-4142-0 pmid:26679180 fatcat:csisrhdoo5ay3kquw2c75cezua