Cirrhosis is a serious and irreversible disease. It is end result of hepatocellular injury that leads to both fibrosis and nodular regeneration. Sub-acute bacterial peritonitis is an important complication. Objective: To determine the frequency of spontaneous bacterial peritonitis (SBP) in cirrhotic patients presenting with hypoalbuminemia. Subject and Methods: This was a Cross sectional study that was conducted at out patient department at DHQ Mandi Bahaudin, BHU Toba and BHU Lurka during July

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... 2018 to December 2018, in which 200 cases selected by non-probability, consecutive sampling were selected. The diagnosis of SBP was made according to standard criteria. Results: Out of total 200 patients in present study, there were 114 males and 94 females with mean age of 49.19±6.671 years. There were 110 cases falling in Child Pugh class C and 90 in Class B. SBP was seen in 60 cases (30%). It was seen in 36 males (31.58%) and 24 females (16.44%) out of their respective groups with p value of 0.69. When SBP was compared with respect to age groups, it also did not reveal any significant difference (p= 0.68). However, significant difference was seen when SBP was seen in different child pugh classes; where out of total 60, there were 44 (40%) in Class C and 16 (17.78%) in class B having p value of 0.02. Conclusion: Chronic liver disease is a high burden disease in low socioeconomic countries like Pakistan. Sub-acute bacterial peritonitis is an important complication and child Pugh class C has a significant association with this. Key Words: SBP, Cirrhosis, hypoalbuminemia.