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Dendritic cells bea ring Langerhans cell (OKT6 +) or interdigi tatin g cell (RFDl +) immunophenotype m ay be reg ularly detected w ithin th e dermis of chronic skin diseases characterized by a lymphohistio cytic (lymphoreticular) infiltrate. T hese 2 subsets of antigen-presenting cell s within the dermis of lesions of exacerbating chronic plaque psoriasis, exacerbating nummul ar dermatitis (dis coid eczema), atopic dermatitis, allergic contact derm atitis, pityriasis [Qsea, li chen ruber planudoi:10.1111/1523-1747.ep12524811 pmid:3734488 fatcat:cluq6vsowjavhpt3hpi6z755qq