Kaposi's Sarcoma-Associated Herpesvirus Infection in the Lung in Multicentric Castleman's Disease

Mitsutoshi HAYASHI, Kazutetsu AOSHIBA, Masahiko SHIMADA, Yutaka IZAWA, Shuji YASUI, Atsushi NAGAI
1999 Internal medicine (Tokyo. 1992)  
A 32-year-old female was admitted for evaluation of multiple infiltrates on a chest radiograph. A diagnosis of multicentric Castleman's disease was made on the basis of typical clinical manifestations. Transbronchial lung biopsy (TBLB) revealed histological findings reported in lymphocytic interstitial pneumonia. Both the polymerase chain reaction and in situ hybridization with a probe specific for Kaposi's sarcoma-associated herpesvirus (KSHV)sequences demonstrated the presence of KSHVin the TBLBsample. (Internal Medicine 38: 279-282, 1999)
doi:10.2169/internalmedicine.38.279 fatcat:25s5f5pu6reuvkrut4ywdjpmyu