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Circulating IL-27 Is Elevated in Rheumatoid Arthritis Patients
2016
Molecules
Cytokines are key immunoregulatory molecules that regulate T lymphocyte-mediated immune responses and inflammatory reactions. We determined whether there is aberrant expression of interleukin-27 (IL-27) in rheumatoid arthritis (RA) patients and investigated the clinical significance of these changes. IL-27 is a key cellular factor that regulates the differentiation of CD4+ T cells, which can secrete interleukin-10 (IL-10) and interleukin-17 (IL-17) in vivo. Concentrations of serum IL-27 in 67
doi:10.3390/molecules21111565
pmid:27869736
fatcat:dk3wgnpprvfxvbp6hwsaso7awi