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In patients with chronic kidney disease, norm chromic normocytic anaemia mainly develops from decreased renal synthesis of erythropoietin. The anaemia becomes more severe as the Glomerular filtration rate (GFR) progressively decreases. No reticulocyte response occurs, red blood cell survival is decreased and there is an associated increased bleeding tendency due to uraemia-induced platelet dysfunction. Untreated anaemia of CKD is strongly associated with cardiovascular and renal complications,fatcat:tchbh4753rcqbktuiitki2wxuu