The research aims to determine the relationship of soil chemical properties (pH, C-organic, and Cation exchange capacity) to the productivity of potato in Karo Regency. The research was started from June till August 2021. The research was conducted using a survey method and soil sampling conducted by stratified random sampling technique (low-high productivity). The 32 samples were taken of 5 sub-districts (Berastagi, Merdeka, Kabanjahe, Tigapanah, Simpangempat) in Karo Regency. Regression tests

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... were performed using the SPSS (Statistical Package for the Social Sciences) version 25 program to obtain the relationship between the soil chemical properties and the productivity of potato (Solanum tuberosum L.). On results research shows that the chemical properties of the soil (pH, C-organic and CEC) simultaneously affected potato productivity by 24.9%. Partially, soil pH has an influence and is correlated with potato (Solanum tuberosum L.) productivity.