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Plastic and Reconstructive Surgery, Global Open
PURPOSE: Current dermal replacement products perform sub-optimally in complex wound beds, such as those that have been irradiated or those with exposed hardware, mostly as a result of insufficient cell invasion and vascularization. We have previously observed more robust endothelial cell invasion of scaffolds containing a micropatterned matrix of differential collagen stiffness in a murine model when compared to collagen controls. Herein we compare the performance of our micropatterneddoi:10.1097/01.gox.0000534039.13447.a4 fatcat:vpoefxgpgvgnzed2vocckzggey