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Mechanisms and Pharmacology of Neuropathic Pain in Multiple Sclerosis
[chapter]
2014
Current topics in behavioral neurosciences
The neuropathic pain of multiple sclerosis is quite prevalent and severely impacts quality of life. A few randomized, placebo-controlled, blinded clinical trials suggest that cannabis-and anticonvulsant-based treatments provide partial pain relief, but at the expense of adverse events. An even smaller, but emerging, number of translational studies are using rodent models of experimental autoimmune encephalomyelitis (EAE), which exhibit pain-like behaviors resembling those of MS patients. These
doi:10.1007/7854_2014_288
pmid:24590824
pmcid:PMC4464806
fatcat:4tph4hdoinah5mgl73qtg4iasq