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Transcriptional Profiling of Host Cell Responses to Virulent Haemophilus parasuis: New Insights into Pathogenesis
2018
International Journal of Molecular Sciences
Haemophilus parasuis is the causative agent of Glässer's disease in pigs. H. parasuis can cause vascular damage, although the mechanism remains unclear. In this study, we investigated the host cell responses involved in the molecular pathway interactions in porcine aortic vascular endothelial cells (PAVECs) induced by H. parasuis using RNA-Seq. The transcriptome results showed that when PAVECs were infected with H. parasuis for 24 h, 281 differentially expressed genes (DEGs) were identified; of
doi:10.3390/ijms19051320
pmid:29710817
pmcid:PMC5983834
fatcat:hzwuvcwhdrehzcqsgwqufx36ua