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Metastatic anal Squamous Cell Carcinoma (SCC) is a relatively uncommon malignancy that is usually treated with palliative platinum based chemotherapy. Response rates are modest and complete responses are rare. Case Report: Here we report on a case of advanced SCC with the extensive visceral metastatic disease that has possibly been cured with chemotherapy alone. The patient has received 6 cycles of Cisplatin and 5FU and has remained in complete remission for over 7 years. Conclusion: This isdoi:10.4236/crcm.2015.43017 fatcat:5z6rz6n3vjbx3bmwg43y5lw3jy